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| # | Name | Team | Date | OPP | DEC | IP | H | R | ER | BB | K | ERA | WHIP | $ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Jacob Misiorowski | MIL | Jun 12 | PHI | W | 9.0 | 1 | 0 | 0 | 0 | 15 | 0.00 | 0.11 | 251.7 | |
| Jesus Luzardo | PHI | Sep 7 | ATL | W | 9.0 | 2 | 0 | 0 | 1 | 12 | 0.00 | 0.33 | 218.4 | |
| Cade Cavalli | WSH | Jun 30 | @BOS | W | 7.0 | 1 | 1 | 0 | 0 | 13 | 0.00 | 0.14 | 216.5 | |
| Dustin May | MIL | Jun 15 | SD | W | 9.0 | 1 | 0 | 0 | 1 | 9 | 0.00 | 0.22 | 210.6 | |
| Dylan Cease | TOR | Jul 25 | @BOS | W | 9.0 | 1 | 0 | 0 | 3 | 12 | 0.00 | 0.44 | 209.9 | |
| Reid Detmers | LAA | Aug 15 | KC | W | 8.0 | 2 | 0 | 0 | 0 | 11 | 0.00 | 0.25 | 209.4 | |
| Eury Perez | MIA | Sep 25 | ATL | W | 9.0 | 1 | 0 | 0 | 1 | 8 | 0.00 | 0.22 | 205.2 | |
| Noah Cameron | KC | Aug 16 | @LAA | W | 9.0 | 1 | 0 | 0 | 1 | 8 | 0.00 | 0.22 | 205.2 | |
| Paul Skenes | PIT | May 12 | COL | W | 8.0 | 2 | 0 | 0 | 0 | 10 | 0.00 | 0.25 | 204.0 | |
| Ranger Suarez | BOS | Apr 27 | @TOR | W | 8.0 | 1 | 0 | 0 | 1 | 10 | 0.00 | 0.25 | 204.0 | |
| Casey Mize | SD | Jun 29 | @NYY | W | 7.0 | 1 | 0 | 0 | 0 | 10 | 0.00 | 0.14 | 200.2 | |
| Bailey Ober | MIN | May 12 | MIA | W | 9.0 | 2 | 0 | 0 | 0 | 7 | 0.00 | 0.22 | 199.7 | |
| Tyler Glasnow | LAD | Apr 23 | @SF | W | 8.0 | 1 | 0 | 0 | 1 | 9 | 0.00 | 0.25 | 198.5 | |
| Eury Perez | MIA | Jul 5 | @ATH | W | 7.0 | 0 | 0 | 0 | 0 | 8 | 0.00 | 0.00 | 198.4 | |
| Drew Rasmussen | TB | Jun 10 | BOS | W | 7.0 | 2 | 0 | 0 | 1 | 13 | 0.00 | 0.43 | 198.3 | |
| Gavin Williams | CLE | Sep 1 | TOR | W | 7.0 | 2 | 1 | 0 | 1 | 13 | 0.00 | 0.43 | 198.3 | |
| Cristopher Sanchez | PHI | May 16 | @PIT | W | 9.0 | 6 | 0 | 0 | 0 | 13 | 0.00 | 0.67 | 198.2 | |
| Cam Schlittler | NYY | Jul 24 | @PHI | W | 7.3 | 3 | 0 | 0 | 0 | 12 | 0.00 | 0.41 | 196.9 | |
| Chris Sale | ATL | Aug 27 | LAD | W | 9.0 | 5 | 0 | 0 | 0 | 11 | 0.00 | 0.56 | 195.9 | |
| Cade Cavalli | WSH | Aug 13 | CHC | W | 8.0 | 1 | 0 | 0 | 2 | 10 | 0.00 | 0.38 | 195.2 | |
| Drew Rasmussen | TB | Jun 5 | @MIA | W | 7.0 | 1 | 0 | 0 | 0 | 9 | 0.00 | 0.14 | 194.8 | |
| Jared Jones | PIT | Sep 22 | STL | W | 7.0 | 1 | 0 | 0 | 0 | 9 | 0.00 | 0.14 | 194.8 | |
| Dylan Cease | TOR | Jul 8 | @SF | W | 8.0 | 1 | 0 | 0 | 3 | 11 | 0.00 | 0.50 | 191.8 | |
| Gavin Williams | CLE | May 22 | @PHI | W | 8.0 | 4 | 0 | 0 | 0 | 11 | 0.00 | 0.50 | 191.8 | |
| Sandy Alcantara | MIA | Apr 1 | CHW | W | 9.0 | 3 | 0 | 0 | 0 | 7 | 0.00 | 0.33 | 191.2 | |
| Max Scherzer | TOR | Aug 30 | SEA | W | 7.0 | 1 | 0 | 0 | 1 | 10 | 0.00 | 0.29 | 191.1 | |
| Bryan Woo | SEA | Sep 6 | ATH | W | 8.0 | 1 | 0 | 0 | 2 | 9 | 0.00 | 0.38 | 189.7 | |
| Jacob deGrom | TEX | Aug 31 | ATH | W | 7.0 | 1 | 0 | 0 | 0 | 8 | 0.00 | 0.14 | 189.3 | |
| Kyle Harrison | MIL | Apr 26 | PIT | W | 6.0 | 1 | 0 | 0 | 1 | 12 | 0.00 | 0.33 | 188.1 | |
| Paul Skenes | PIT | May 6 | @ARI | W | 8.0 | 2 | 0 | 0 | 0 | 7 | 0.00 | 0.25 | 187.7 | |
| Logan Gilbert | SEA | Jul 4 | TOR | W | 7.3 | 1 | 0 | 0 | 0 | 7 | 0.00 | 0.14 | 187.7 | |
| Kris Bubic | LAD | Apr 10 | CHW | W | 7.0 | 2 | 0 | 0 | 1 | 11 | 0.00 | 0.43 | 187.4 | |
| Kyle Harrison | MIL | May 20 | @CHC | W | 7.0 | 2 | 0 | 0 | 1 | 11 | 0.00 | 0.43 | 187.4 | |
| Yoshinobu Yamamoto | LAD | Jun 13 | @CHW | W | 8.3 | 1 | 1 | 1 | 0 | 7 | 1.08 | 0.12 | 187.3 | |
| Brandon Sproat | MIL | Jun 23 | @CIN | W | 6.0 | 1 | 0 | 0 | 0 | 10 | 0.00 | 0.17 | 186.7 | |
| Braxton Ashcraft | PIT | Aug 13 | @MIA | W | 9.0 | 3 | 1 | 1 | 1 | 10 | 1.00 | 0.44 | 186.5 | |
| Michael Wacha | KC | Aug 28 | @CLE | W | 8.0 | 4 | 0 | 0 | 0 | 10 | 0.00 | 0.50 | 186.4 | |
| Cristopher Sanchez | PHI | May 5 | ATH | W | 8.0 | 3 | 0 | 0 | 1 | 10 | 0.00 | 0.50 | 186.4 | |
| Drew Rasmussen | TB | Jul 26 | CLE | W | 7.0 | 1 | 0 | 0 | 1 | 9 | 0.00 | 0.29 | 185.6 | |
| Bryan Woo | SEA | May 30 | ARI | W | 7.0 | 2 | 0 | 0 | 0 | 9 | 0.00 | 0.29 | 185.6 | |
| Payton Tolle | BOS | Aug 7 | ATH | W | 6.0 | 2 | 1 | 1 | 0 | 14 | 1.50 | 0.33 | 185.1 | |
| Carlos Rodon | NYY | Sep 22 | TB | W | 8.0 | 3 | 0 | 0 | 0 | 8 | 0.00 | 0.38 | 184.3 | |
| Paul Skenes | PIT | Apr 24 | @MIL | W | 7.0 | 1 | 0 | 0 | 0 | 7 | 0.00 | 0.14 | 183.9 | |
| Hunter Greene | CIN | Jul 10 | CHC | W | 7.0 | 3 | 0 | 0 | 1 | 12 | 0.00 | 0.57 | 183.7 | |
| Jose Soriano | TOR | Apr 6 | ATL | W | 8.0 | 3 | 1 | 1 | 0 | 10 | 1.13 | 0.38 | 182.2 | |
| Jacob deGrom | TEX | May 10 | CHC | W | 7.0 | 3 | 0 | 0 | 0 | 10 | 0.00 | 0.43 | 182.0 | |
| Luis Castillo | CHW | Aug 12 | CIN | W | 7.0 | 1 | 0 | 0 | 2 | 10 | 0.00 | 0.43 | 182.0 | |
| Tarik Skubal | LAD | Sep 25 | @SF | W | 7.0 | 3 | 0 | 0 | 0 | 10 | 0.00 | 0.43 | 182.0 | |
| Justin Wrobleski | LAD | May 29 | PHI | W | 7.0 | 1 | 1 | 1 | 0 | 9 | 1.29 | 0.14 | 181.4 | |
| Emerson Hancock | SEA | Mar 29 | CLE | W | 6.0 | 0 | 0 | 0 | 1 | 9 | 0.00 | 0.17 | 181.3 | |
| Zack Wheeler | PHI | Jul 7 | @CIN | W | 7.0 | 4 | 1 | 1 | 0 | 14 | 1.29 | 0.57 | 181.2 | |
| Jesus Luzardo | PHI | Apr 28 | SF | W | 7.0 | 2 | 0 | 0 | 0 | 8 | 0.00 | 0.29 | 180.2 | |
| Bryce Miller | SEA | Jul 2 | LAA | W | 7.0 | 2 | 0 | 0 | 0 | 8 | 0.00 | 0.29 | 180.2 | |
| Payton Tolle | BOS | May 4 | @DET | W | 7.0 | 1 | 2 | 0 | 1 | 8 | 0.00 | 0.29 | 180.2 | |
| Jacob Misiorowski | MIL | May 25 | STL | W | 7.0 | 2 | 1 | 1 | 1 | 12 | 1.29 | 0.43 | 179.5 | |
| Jesus Luzardo | PHI | Jul 9 | @CIN | W | 7.0 | 2 | 0 | 0 | 2 | 11 | 0.00 | 0.57 | 178.3 | |
| Jacob deGrom | TEX | Aug 20 | WSH | W | 6.0 | 1 | 0 | 0 | 1 | 10 | 0.00 | 0.33 | 177.3 | |
| Max Meyer | MIA | May 2 | PHI | W | 7.0 | 1 | 0 | 0 | 1 | 7 | 0.00 | 0.29 | 174.8 | |
| Hunter Brown | HOU | Jul 25 | @CHW | W | 7.0 | 2 | 0 | 0 | 0 | 7 | 0.00 | 0.29 | 174.8 | |
| Brandon Pfaadt | ARI | Aug 14 | @ATL | W | 7.0 | 2 | 0 | 0 | 0 | 7 | 0.00 | 0.29 | 174.8 | |
| Cam Schlittler | NYY | Jun 19 | CIN | W | 6.0 | 4 | 0 | 0 | 0 | 13 | 0.00 | 0.67 | 174.7 | |
| Sean Manaea | NYM | Aug 9 | @PIT | W | 7.0 | 3 | 1 | 1 | 0 | 11 | 1.29 | 0.43 | 174.0 | |
| Gavin Williams | CLE | Aug 2 | ARI | W | 5.7 | 1 | 0 | 0 | 1 | 10 | 0.00 | 0.35 | 172.9 | |
| Mick Abel | MIN | Apr 14 | BOS | W | 7.0 | 4 | 0 | 0 | 0 | 10 | 0.00 | 0.57 | 172.9 | |
| Max Fried | NYY | Apr 22 | @BOS | W | 8.0 | 3 | 0 | 0 | 2 | 9 | 0.00 | 0.63 | 172.1 | |
| Chris Sale | ATL | Jul 29 | @NYM | W | 6.0 | 2 | 0 | 0 | 0 | 9 | 0.00 | 0.33 | 171.8 | |
| Reid Detmers | LAA | Sep 8 | @BOS | W | 6.0 | 1 | 0 | 0 | 1 | 9 | 0.00 | 0.33 | 171.8 | |
| Nathan Eovaldi | TEX | May 6 | @NYY | W | 8.0 | 3 | 1 | 1 | 0 | 8 | 1.13 | 0.38 | 171.4 | |
| Jacob Misiorowski | MIL | May 31 | @HOU | W | 7.0 | 3 | 0 | 0 | 0 | 8 | 0.00 | 0.43 | 171.1 | |
| Andre Pallante | STL | Jul 25 | CIN | W | 7.0 | 2 | 0 | 0 | 1 | 8 | 0.00 | 0.43 | 171.1 | |
| Jared Jones | PIT | Sep 10 | @CHW | W | 7.0 | 1 | 0 | 0 | 2 | 8 | 0.00 | 0.43 | 171.1 | |
| Logan Henderson | MIL | Aug 28 | TEX | W | 7.0 | 1 | 1 | 1 | 0 | 7 | 1.29 | 0.14 | 170.5 | |
| Drew Rasmussen | TB | Apr 12 | NYY | W | 6.0 | 1 | 0 | 0 | 0 | 7 | 0.00 | 0.17 | 170.4 | |
| Chris Sale | ATL | Jul 17 | TEX | W | 7.0 | 2 | 0 | 0 | 0 | 6 | 0.00 | 0.29 | 169.3 | |
| Jacob Misiorowski | MIL | Jul 26 | COL | W | 5.0 | 1 | 1 | 1 | 0 | 12 | 1.80 | 0.20 | 168.7 | |
| Cam Schlittler | NYY | Sep 8 | COL | W | 7.0 | 3 | 1 | 1 | 0 | 10 | 1.29 | 0.43 | 168.6 | |
| Gerrit Cole | NYY | May 27 | @KC | W | 6.7 | 4 | 0 | 0 | 0 | 10 | 0.00 | 0.60 | 168.6 | |
| Logan Gilbert | SEA | Jun 16 | BAL | W | 7.0 | 2 | 1 | 1 | 1 | 10 | 1.29 | 0.43 | 168.6 | |
| Taj Bradley | MIN | Jul 7 | CLE | W | 7.0 | 3 | 1 | 1 | 0 | 10 | 1.29 | 0.43 | 168.6 | |
| Gavin Williams | CLE | Apr 29 | TB | W | 7.7 | 5 | 1 | 0 | 0 | 9 | 0.00 | 0.65 | 168.1 | |
| Noah Cameron | KC | Aug 5 | MIN | W | 8.0 | 3 | 1 | 1 | 1 | 9 | 1.13 | 0.50 | 168.0 | |
| Tatsuya Imai | HOU | Jun 25 | @DET | W | 6.0 | 2 | 0 | 0 | 1 | 10 | 0.00 | 0.50 | 167.8 | |
| Cristopher Sanchez | PHI | Mar 26 | TEX | W | 6.0 | 3 | 0 | 0 | 0 | 10 | 0.00 | 0.50 | 167.8 | |
| Dylan Cease | TOR | Jul 3 | @SEA | W | 7.0 | 3 | 0 | 0 | 1 | 9 | 0.00 | 0.57 | 167.4 | |
| Joe Ryan | MIN | Jul 5 | @NYY | W | 7.0 | 3 | 0 | 0 | 1 | 9 | 0.00 | 0.57 | 167.4 | |
| Jesus Luzardo | PHI | Aug 26 | @SEA | W | 7.0 | 1 | 0 | 0 | 3 | 9 | 0.00 | 0.57 | 167.4 | |
| Gavin Williams | CLE | Sep 20 | ATH | W | 7.0 | 3 | 0 | 0 | 1 | 9 | 0.00 | 0.57 | 167.4 | |
| Tarik Skubal | LAD | Jun 30 | @NYY | W | 6.0 | 1 | 2 | 1 | 0 | 9 | 1.50 | 0.17 | 167.4 | |
| Tarik Skubal | LAD | Sep 14 | @CIN | W | 7.0 | 3 | 0 | 0 | 1 | 9 | 0.00 | 0.57 | 167.4 | |
| Mitch Bratt | ARI | Aug 5 | SD | W | 7.0 | 1 | 0 | 0 | 3 | 9 | 0.00 | 0.57 | 167.4 | |
| Nolan McLean | NYM | Jun 17 | @CIN | W | 7.0 | 3 | 1 | 0 | 1 | 9 | 0.00 | 0.57 | 167.4 | |
| Bryan Woo | SEA | Jun 18 | BAL | W | 7.0 | 3 | 0 | 0 | 1 | 9 | 0.00 | 0.57 | 167.4 | |
| Trevor McDonald | SF | May 4 | SD | W | 7.0 | 2 | 1 | 1 | 0 | 8 | 1.29 | 0.29 | 166.8 | |
| Ryan Johnson | LAA | Jun 23 | BAL | W | 6.0 | 1 | 0 | 0 | 1 | 8 | 0.00 | 0.33 | 166.4 | |
| Trey Yesavage | TOR | May 20 | @NYY | W | 6.0 | 2 | 0 | 0 | 0 | 8 | 0.00 | 0.33 | 166.4 | |
| Cam Schlittler | NYY | Mar 27 | @SF | W | 5.3 | 1 | 0 | 0 | 0 | 8 | 0.00 | 0.19 | 165.8 | |
| Payton Tolle | BOS | Jun 26 | NYY | W | 7.0 | 1 | 0 | 0 | 2 | 7 | 0.00 | 0.43 | 165.7 | |
| Kade Anderson | SEA | Sep 20 | @COL | W | 7.0 | 3 | 0 | 0 | 0 | 7 | 0.00 | 0.43 | 165.7 | |
| Yoshinobu Yamamoto | LAD | Sep 15 | @CIN | W | 7.0 | 1 | 0 | 0 | 2 | 7 | 0.00 | 0.43 | 165.7 | |
| Cam Schlittler | NYY | Apr 1 | @SEA | W | 6.3 | 2 | 0 | 0 | 0 | 7 | 0.00 | 0.32 | 165.2 |
