Take Arenado for Gattis and run.
Ramos is a power hitter with a wrist injury. Drop him until he proves you should pick him up. Mesoraco is a tougher call but I would probably drop him in a 1 catcher league.
I think you'll have to keep Trumbo, Cobb, Anibal, and some others.
12-teamer, H2H, points, 4 keepers.
Hitters: +1 single, +2 dbl, +3 trpl, +4 HR, +1 RBI, +1 run, +1 BB/HBP, -1 K, +2 SB, -1 CS
Pitchers: +1.5 IP, +1 K, -1 BB/HBP, +5 W, -3 L, +4 S, -2 BS, +3 CG, +10 shutout
Start one player at each position + utility, 4 SPs, 2 RPs. 8 reserves.
C: Y. Molina
SS: Al. Ramirez
OF: Bautista, Corey Dickerson, & one of R. Castillo, Fowler, Snider
U: one of Pearce, R. Castillo, Fowler, Snider, Jung Ho Kang
SP: four of J. Shields, Iwakuma, P. Hughes, A. Sanchez, Ryu, Shoemaker, S. Miller, Jon Gray
RP: two of D. Robertson, C. Allen & A. Miller