The league is 10 team H2H, with: QB, RB, RB, WR, WR, W/R, W/T, TE, Def. Having kept Matt Schaub for a 12th rounder and Steve Slaton for a 17th, I am now looking at the 4th pick overall. Based on your rankings, the top five available go:
2) Jones Drew
5) R. Moss
After that, most of the big name receivers are available, including A Johnson, S Smith, R Wayne, Boldin, Colston, and Marshall (Fitzy, C Johnson, Jennings, White, Bowe all kept), as well as the big name QB's, including Brees, Brady, and Peyton. I imagine those WR's will be moving pretty quickly off the board, but im not sure.
Is my best bet to grab the best available RB in that top 5 and grabbing best available WR on my next pick? Or should I snag Moss or Johnson right away and see what happens next round?
i'd definitely go with any of those RB's. Then you can stock up on WR's the next 3-4 rounds knowing you have 2 top 10 RB's. In the 2nd round you should still be able to get Boldin/Colston/Marshall. Maybe even 2 of them.